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Pathogens Free Full-Text Host-Directed Therapies for Tuberculosis
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Therapeutic host-directed strategies to improve outcome in
WebJul 21, 2024 · HDT alone might never be enough to contain and clear M. tuberculosis bacilli in an active TB patient, but incorporating this treatment class will certainly increase the effect of our currently available anti-mycobacterial drugs, and might give our immune system the little push it needs to efficiently contain M. tuberculosis infection. WebNov 26, 2024 · We present a comprehensive, up-to-date review of host-directed therapeutics (HDTs) to improve clinical outcome in tuberculosis (TB) disease, summarizing all compounds, primarily repurposed drugs ... WebAug 26, 2024 · This can contribute to the development of drug-resistant Mycobacteria tuberculosis (Mtb), multi-drug-resistant (MDR) and extensive drug-resistant (XDR) strains . Host-directed therapy (HDT) is an emerging concept in the treatment of TB, aimed at directly modulating host cell functions, and is administered in addition to antimicrobial treatment. is hetty smaller than henry