Webb16 dec. 2024 · This prospective study evaluated the liver enzyme elevation during statin therapy in very elderly patients (≥80 years old). Methods Patients with hypercholesterolemia (LDL-C levels ≥3.4 and < 5.7 mmol/L), atherosclerosis, coronary heart disease (CHD), or a CHD-risk equivalent were enrolled and received once-daily statin … WebbIn older adults, statins can also cause: Falls Memory loss and confusion Nausea, constipation, or diarrhea. Often, older adults take many drugs. These can interact with statins and lead to serious problems. Side effects, like muscle pain, may increase. Statins can also cause a fatal reaction when taken with heart-rhythm drugs.
Appropriateness of statins in patients aged ≥80 years and comparison to other age groups
Webb27 aug. 2024 · The researchers noted that the lower risk of death for new statin users remained significant even among veterans over 90 years old and even among veterans who had dementia. It is important to consider that because 97% of the veterans in the study were men and 91% of the veterans were white, these results may not apply to women or … Webb10 feb. 2024 · Statins are frequently initiated in patients aged 80 years and older after an ischemic stroke, even though evidence on prevention of recurrent cardiovascular … business a level questions by topic
Should Statins Be Started in Patients Over 80? - MPR
Webb2 okt. 2024 · Statin drugs have been shown to reduce the risk of cardiovascular disease (CVD) in young and middle-aged adults. With older adults (those 75 and over), the benefits are less clear. But a recent study published in the European Heart Journal suggests that there is in fact a benefit to statin use in this older population. Webb1 nov. 2009 · In the A to Z trial, a little over 2,200 patients with acute coronary syndrome were randomized to placebo for 4 months and then 20 mg simvastatin (standard therapy) or aggressively with 40 mg simvastatin for 1 month starting immediately after enrollment and then increased to 80 mg. Follow-up was for at least 6 months and up to 24 months. Webb31 maj 2016 · This includes moderate-intensity statins such as daily atorvastatin 20 mg, rosuvastatin 10 mg, simvastatin 40 mg, pravastatin 40 mg, fluvastatin 80 mg, or pitavastatin 2 mg. 3. Fibrates should be avoided in combination with statins in patients with CKD, and ezetimibe monotherapy is not recommended. Since drug toxicity is less of a … handmaid\u0027s tale season 5 mrs wheeler